The Renal and Reproductive Physiology Lab is a NIH (HL114096, HL109843) and AHA (10SDG2600040) funded laboratory that studies a number of women’s health and fetal/child development issues. Our primary focus in on developing an better understanding of the mechanisms underlying the pathophysiology of the hypertension and fetal growth restriction associated with preeclamptic pregnancies. Currently funded projects include investigations into: 1) the role of exercise as a means to minimize the effects of placental ischemia on maternal cardiovascular function (PI); 2) the role of angiogenic factors in the regulation of cardiovascular and renal function during hypertension and pregnancy (PI); 3) the role of complement activation on angiogenic balance during pregnancy (Co-I with J Regal); 4) the role of angiogenic factors in fetal programming of disease (PI and co-I).
Check out the Recent News link to find out about recent happenings in the lab. The links for Lab members and Alumni have information about current and former lab members. The newsletter for the American Physiological Society Water and Electrolyte Section is here.
Interested in training opportunities in the Renal-Repro Lab? Click Here.
Check out the nice story on Chris Banek of the Renal-Repro Lab.
Recent Publications
AICAR (5-aminoimidazole-4-carboxamide-3-ribonucleoside) administration ameliorates hypertension and angiogenic imbalance in a model of preeclampsia in the rat. Christopher T Banek, Ashley J Bauer, Karen M Needham, Hans C. Dreyer, and Jeffrey S Gilbert
Diabetes in Early Pregnancy: Getting to the Heart of the Matter
Jeffrey S. Gilbert, Christopher T. Banek, Sara A. Babcock & Hans C. Dreyer
Diabetes January 2013 62:27-28
Exercise Training Attenuates Placental Ischemia-Induced Hypertension and Angiogenic Imbalance in the Rat
Jeffrey S. Gilbert, Christopher T. Banek, Ashley J. Bauer, Anne Gingery, and Karen Needham
Hypertension 2012; first published on October 22 2012 asdoi:10.1161/HYPERTENSIONAHA.112.202275
Complement Activation in Pregnancy: Too Much of a Good Thing?
- Jeffrey S. Gilbert, Christopher T. Banek, Vern L. Katz, Sara A. Babcock, and Jean F. Regal
Hypertension 2012; first published on September 24 2012 asdoi:10.1161/HYPERTENSIONAHA.112.202747
Timing of ischemic insult alters fetal growth trajectory, maternal angiogenic balance, and markers of renal oxidative stress in the pregnant rat
Christopher T. Banek, Ashley J. Bauer, Anne Gingery, and Jeffrey S. Gilbert
Am J Physiol Regul Integr Comp Physiol September 15, 2012 303:R658-R664; published ahead of print July 25, 2012, doi:10.1152/ajpregu.00250.2012
Placental and vascular adaptations to exercise training before and during pregnancy in the rat
Jeffrey S. Gilbert, Christopher T. Banek, Ashley J. Bauer, Anne Gingery and Hans C. Dreyer
Am J Physiol Regul Integr Comp Physiol September 1, 2012303:R520-R526; published ahead of print July 18, 2012,doi:10.52/ajpregu.00253.2012
The Department of Human Physiology at the University of Oregon is searching for 2 faculty positions this fall.
1) An Integrative Physiologist (review of applications begins Oct 15)
2) A Neurophysiologist (review of applications begins Nov 15)
